Low Density Lipoprotein Receptor-related Protein-1 (LRP1) Regulates Thrombospondin-2 (TSP2) Enhancement of Notch3 Signaling

Intracellular trafficking of Notch and Notch ligands modulates signaling, suggesting that choreography of ligand and receptor translocation is essential for optimal Notch activity. Indeed, a major model for Notch signaling posits that Notch trans-endocytosis into the ligand-expressing (signal sendin...

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Hlavní autoři: Meng, He, Zhang, Xiaojie, Lee, Soo Jung, Strickland, Dudley K., Lawrence, Daniel A., Wang, Michael M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906298/
https://ncbi.nlm.nih.gov/pubmed/20472562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.144634
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