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Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1
Thrombospondin-1 (TSP1) has potent biological effects on vasculature smooth muscle cells (SMCs) and endothelial cells. The regulation of extracellular accumulation of TSP1 is mediated by a previously obscure process of endocytosis which leads to its lysosomal degradation. Since members of the low de...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1995
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2120467/ https://ncbi.nlm.nih.gov/pubmed/7775583 |
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