Molecular Basis for the Interaction of Low Density Lipoprotein Receptor-related Protein 1 (LRP1) with Integrin α(M)β(2): IDENTIFICATION OF BINDING SITES WITHIN α(M)β(2) FOR LRP1

The LDL receptor-related protein 1 (LRP1) is a large endocytic receptor that controls macrophage migration in part by interacting with β(2) integrin receptors. However, the molecular mechanism underlying LRP1 integrin recognition is poorly understood. Here, we report that LRP1 specifically recognize...

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Autores principales: Ranganathan, Sripriya, Cao, Chunzhang, Catania, Jason, Migliorini, Molly, Zhang, Li, Strickland, Dudley K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162413/
https://ncbi.nlm.nih.gov/pubmed/21676865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.265413
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