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Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Forms a Signaling Complex with Platelet-derived Growth Factor Receptor-β in Endosomes and Regulates Activation of the MAPK Pathway

In addition to its endocytic function, the low density lipoprotein receptor-related protein 1 (LRP1) also contributes to cell signaling events. In the current study, the potential of LRP1 to modulate the platelet-derived growth factor (PDGF) signaling pathway was investigated. PDGF is a key regulato...

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Detalhes bibliográficos
Main Authors: Muratoglu, Selen Catania, Mikhailenko, Irina, Newton, Christopher, Migliorini, Mary, Strickland, Dudley K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863204/
https://ncbi.nlm.nih.gov/pubmed/20220145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046672
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