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LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages

Within the circulation, cholesterol is transported by lipoprotein particles and is taken up by cells when these particles associate with cellular receptors. In macrophages, excessive lipoprotein particle uptake leads to foam cell formation, which is an early event in the development of atheroscleros...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Lillis, Anna P., Muratoglu, Selen Catania, Au, Dianaly T., Migliorini, Mary, Lee, Mi-Jeong, Fried, Susan K., Mikhailenko, Irina, Strickland, Dudley K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463855/
https://ncbi.nlm.nih.gov/pubmed/26061292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128903
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