LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages

Within the circulation, cholesterol is transported by lipoprotein particles and is taken up by cells when these particles associate with cellular receptors. In macrophages, excessive lipoprotein particle uptake leads to foam cell formation, which is an early event in the development of atheroscleros...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lillis, Anna P., Muratoglu, Selen Catania, Au, Dianaly T., Migliorini, Mary, Lee, Mi-Jeong, Fried, Susan K., Mikhailenko, Irina, Strickland, Dudley K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463855/
https://ncbi.nlm.nih.gov/pubmed/26061292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128903
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