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LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages
Within the circulation, cholesterol is transported by lipoprotein particles and is taken up by cells when these particles associate with cellular receptors. In macrophages, excessive lipoprotein particle uptake leads to foam cell formation, which is an early event in the development of atheroscleros...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4463855/ https://ncbi.nlm.nih.gov/pubmed/26061292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128903 |
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