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LRP1: Role in the regulation of vascular integrity
LRP1 is a large endocytic and signaling receptor that is widely expressed. In the liver, LRP1 plays an important role in regulating the plasma levels of blood coagulation factor VIII (fVIII) by mediating its uptake and subsequent degradation. fVIII is a key plasma protein that is deficient in Hemoph...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4304649/ https://ncbi.nlm.nih.gov/pubmed/24504736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.301924 |
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