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Seamless Bead to Microarray Screening: Rapid Identification of the Highest Affinity Protein Ligands From Large Combinatorial Libraries
Several approaches have been developed for screening combinatorial libraries or collections of synthetic molecules for agonists or antagonists of protein function, each with its own advantages and limitations. In this report, we describe an experimental platform that seamlessly couples massively par...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905650/ https://ncbi.nlm.nih.gov/pubmed/20142039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2009.12.015 |
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