Protein kinase C-θ mediates negative feedback on regulatory T cell function

T cell receptor (TCR) dependent regulatory T cell (Treg) activity controls effector T cell (Teff) function and is inhibited by the inflammatory cytokine tumor necrosis factor (TNF)-α. Protein kinase C-θ (PKC-θ) recruitment to the immunological synapse is required for full Teff activation. In contras...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zanin-Zhorov, Alexandra, Ding, Yi, Kumari, Sudha, Attur, Mukundan, Hippen, Keli L., Brown, Maryanne, Blazar, Bruce R., Abramson, Steven B., Lafaille, Juan J., Dustin, Michael L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905626/
https://ncbi.nlm.nih.gov/pubmed/20339032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1186068
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia