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Human in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity
In vitro induced human regulatory T cells (iTregs) have demonstrated in vivo therapeutic utility, but pathways regulating their function have not been elucidated. Here, we report that human iTregs generated in vitro from naïve cord blood cells preferentially recruit Disc large homolog 1 (Dlgh1) and...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484704/ https://ncbi.nlm.nih.gov/pubmed/28652577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04053-5 |
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