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NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU)

Picornaviruses have a 22–24 amino acid peptide, VPg, bound covalently at the 5’ end of their RNA, that is essential for replication. VPgs are uridylylated at a conserved Tyrosine to form VPgpU, the primer of RNA synthesis by the viral polymerase. This first complete structure for any uridylylated VP...

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Bibliografski detalji
Glavni autori: Schein, Catherine H., Oezguen, Numan, van der Heden van Noort, Gerbrand J., Filippov, Dmitri V., Paul, Aniko, Kumar, Eric, Braun, Werner
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905501/
https://ncbi.nlm.nih.gov/pubmed/20441784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.04.021
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