DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis

Epigenetic changes are among the most common alterations observed in cancer cells, yet the mechanism by which cancer cells acquire and maintain abnormal DNA methylation patterns is not understood. Cancer cells have an altered distribution of DNA methylation and express aberrant DNA methyltransferase...

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Main Authors: Shah, Mrinal Y., Vasanthakumar, Aparna, Barnes, Natalie Y., Figueroa, Maria E., Kamp, Anna, Hendrick, Christopher, Ostler, Kelly R., Davis, Elizabeth M., Lin, Shang, Anastasi, John, Le Beau, Michelle M., Moskowitz, Ivan, Melnick, Ari, Pytel, Peter, Godley, Lucy A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905468/
https://ncbi.nlm.nih.gov/pubmed/20587527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0847
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