Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins

Cancer cells display an altered distribution of DNA methylation relative to normal cells. Certain tumor suppressor gene promoters are hypermethylated and transcriptionally inactivated, whereas repetitive DNA is hypomethylated and transcriptionally active. Little is understood about how the abnormal...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Ostler, KR, Davis, EM, Payne, SL, Gosalia, BB, Expósito-Céspedes, J, Le Beau, MM, Godley, LA
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435620/
https://ncbi.nlm.nih.gov/pubmed/17353906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210351
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