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Cancer cells express aberrant DNMT3B transcripts encoding truncated proteins
Cancer cells display an altered distribution of DNA methylation relative to normal cells. Certain tumor suppressor gene promoters are hypermethylated and transcriptionally inactivated, whereas repetitive DNA is hypomethylated and transcriptionally active. Little is understood about how the abnormal...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435620/ https://ncbi.nlm.nih.gov/pubmed/17353906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210351 |
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