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Betulinic acid induces apoptosis and inhibits hedgehog signalling in rhabdomyosarcoma
BACKGROUND: Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in childhood with the ability to resist apoptosis by the activation of survival promoting and anti-apoptotic proteins. METHODS: Efficacy of the apoptosis-inducing agent betulinic acid (BA) was determined in RMS cell cultures a...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905279/ https://ncbi.nlm.nih.gov/pubmed/20517313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605715 |
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