Betulinic acid inhibits autophagic flux and induces apoptosis in human multiple myeloma cells in vitro

AIM: To investigate the effects of betulinic acid (BA) on apoptosis and autophagic flux in multiple myeloma cells and the relationship between the two processes. METHODS: The proliferation of human multiple myeloma KM3 cells was measured with MTT assay. FITC/PI double-labeled flow cytometry (FCM) an...

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Detalhes bibliográficos
Main Authors: Yang, Li-jing, Chen, Yan, He, Jing, Yi, Sha, Wen, Lu, Zhao, Jie, Zhang, Ben-ping, Cui, Guo-hui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001834/
https://ncbi.nlm.nih.gov/pubmed/23064721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.102
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