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Topoisomerase I regulates open chromatin and controls gene expression in vivo

DNA topoisomerases regulate the topological state of the DNA double helix and are key enzymes in the processes of DNA replication, transcription and genome stability. Using the fission yeast model Schizosaccharomyces pombe, we investigate genome wide how DNA topoisomerases I and II affect chromatin...

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Bibliografiska uppgifter
Huvudupphovsmän: Durand-Dubief, Mickaël, Persson, Jenna, Norman, Ulrika, Hartsuiker, Edgar, Ekwall, Karl
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905247/
https://ncbi.nlm.nih.gov/pubmed/20526281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.109
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