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Topoisomerase I regulates open chromatin and controls gene expression in vivo
DNA topoisomerases regulate the topological state of the DNA double helix and are key enzymes in the processes of DNA replication, transcription and genome stability. Using the fission yeast model Schizosaccharomyces pombe, we investigate genome wide how DNA topoisomerases I and II affect chromatin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905247/ https://ncbi.nlm.nih.gov/pubmed/20526281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.109 |
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