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Topoisomerases, chromatin and transcription termination

In eukaryotes transcription is complicated by the DNA being packed in nucleosomes and by supercoils induced by opening of the DNA double helix during elongation. Here we discuss our recent genome-wide work regarding topoisomerases and their role in chromatin remodeling during the transcription cycle...

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Detalhes bibliográficos
Main Authors: Durand-Dubief, Mickaël, Svensson, J Peter, Persson, Jenna, Ekwall, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062396/
https://ncbi.nlm.nih.gov/pubmed/21468231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.2.2.14411
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