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Copy number of 8q24.3 drives HSF1 expression and patient outcome in cancer: an individual patient data meta-analysis

BACKGROUND: The heat-shock transcription factor 1 (HSF1) has been linked to cell proliferation and survival in cancer and has been proposed as a biomarker for poor prognosis. Here, we assessed the role of HSF1 expression in relation to copy number alteration (CNA) and cancer prognosis. METHODS: Usin...

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Detalhes bibliográficos
Publicado no:Hum Genomics
Main Authors: Brusselaers, Nele, Ekwall, Karl, Durand-Dubief, Mickael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6836670/
https://ncbi.nlm.nih.gov/pubmed/31699156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40246-019-0241-3
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