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Mechanism of Holliday junction resolution by the human GEN1 protein
Holliday junction (HJ) resolution is essential for chromosome segregation at meiosis and the repair of stalled/collapsed replication forks in mitotic cells. All organisms possess nucleases that promote HJ resolution by the introduction of symmetrically related nicks in two strands at, or close to, t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904945/ https://ncbi.nlm.nih.gov/pubmed/20634321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.585310 |
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