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Aberrant chromosome morphology in human cells defective for Holliday junction resolution

In somatic cells, Holliday junctions can be formed between sister chromatids during the recombinational repair of DNA breaks or after replication fork demise. A variety of processes act upon Holliday junctions to remove them from DNA, in events that are critical for proper chromosome segregation. In...

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Main Authors: Wechsler, Thomas, Newman, Scott, West, Stephen C.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560329/
https://ncbi.nlm.nih.gov/pubmed/21399624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09790
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