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Aberrant chromosome morphology in human cells defective for Holliday junction resolution

In somatic cells, Holliday junctions can be formed between sister chromatids during the recombinational repair of DNA breaks or after replication fork demise. A variety of processes act upon Holliday junctions to remove them from DNA, in events that are critical for proper chromosome segregation. In...

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Autori principali: Wechsler, Thomas, Newman, Scott, West, Stephen C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3560329/
https://ncbi.nlm.nih.gov/pubmed/21399624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09790
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