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Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities

Enzymatic activities that cleave Holliday junctions are required for the resolution of recombination intermediates and for the restart of stalled replication forks. Here we show that human cell-free extracts possess two distinct endonucleases that can cleave Holliday junctions. The first cleaves Hol...

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書目詳細資料
Main Authors: Constantinou, Angelos, Chen, Xiao-Bo, McGowan, Clare H., West, Stephen C.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC129086/
https://ncbi.nlm.nih.gov/pubmed/12374758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf554
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