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Bacterial-type DNA Holliday junction resolvases in eukaryotic viruses

Homologous DNA recombination promotes genetic diversity and the maintenance of genome integrity, yet no enzymes with specificity for the Holliday junction (HJ)—a key DNA recombination intermediate—have been purified and characterized from metazoa or their viruses. Here we identify critical structura...

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Bibliographic Details
Main Authors: Garcia, Alonzo D., Aravind, L., Koonin, Eugene V., Moss, Bernard
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC16798/
https://ncbi.nlm.nih.gov/pubmed/10890916
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