A method for preparing genomic DNA that restrains branch migration of Holliday junctions
The Holliday junction is a central intermediate in genetic recombination. This four-stranded DNA structure is capable of spontaneous branch migration, and is lost during standard DNA extraction protocols. In order to isolate and characterize recombination intermediates that contain Holliday junction...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10606674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.2.e6 |
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