A method for preparing genomic DNA that restrains branch migration of Holliday junctions
The Holliday junction is a central intermediate in genetic recombination. This four-stranded DNA structure is capable of spontaneous branch migration, and is lost during standard DNA extraction protocols. In order to isolate and characterize recombination intermediates that contain Holliday junction...
Guardat en:
| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102538/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10606674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.2.e6 |
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