Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities

Enzymatic activities that cleave Holliday junctions are required for the resolution of recombination intermediates and for the restart of stalled replication forks. Here we show that human cell-free extracts possess two distinct endonucleases that can cleave Holliday junctions. The first cleaves Hol...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Constantinou, Angelos, Chen, Xiao-Bo, McGowan, Clare H., West, Stephen C.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2002
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129086/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12374758/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf554
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