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Mechanism of Holliday junction resolution by the human GEN1 protein

Holliday junction (HJ) resolution is essential for chromosome segregation at meiosis and the repair of stalled/collapsed replication forks in mitotic cells. All organisms possess nucleases that promote HJ resolution by the introduction of symmetrically related nicks in two strands at, or close to, t...

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Detalhes bibliográficos
Main Authors: Rass, Ulrich, Compton, Sarah A., Matos, Joao, Singleton, Martin R., Ip, Stephen C.Y., Blanco, Miguel G., Griffith, Jack D., West, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904945/
https://ncbi.nlm.nih.gov/pubmed/20634321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.585310
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