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Nonsense-mediated mRNA decay maintains translational fidelity by limiting magnesium uptake
Inactivation of the yeast nonsense-mediated mRNA decay (NMD) pathway stabilizes nonsense mRNAs and promotes readthrough of premature translation termination codons. Although the latter phenotype is thought to reflect a direct role of NMD factors in translation termination, its mechanism is unknown....
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904939/ https://ncbi.nlm.nih.gov/pubmed/20634315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1930710 |
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