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Nonsense-mediated mRNA decay maintains translational fidelity by limiting magnesium uptake

Inactivation of the yeast nonsense-mediated mRNA decay (NMD) pathway stabilizes nonsense mRNAs and promotes readthrough of premature translation termination codons. Although the latter phenotype is thought to reflect a direct role of NMD factors in translation termination, its mechanism is unknown....

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Autors principals: Johansson, Marcus J.O., Jacobson, Allan
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904939/
https://ncbi.nlm.nih.gov/pubmed/20634315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1930710
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