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Aggregation of deamidated human βB2-crystallin and incomplete rescue by α-crystallin chaperone
Aging of the lens is accompanied by extensive deamidation of the lens specific proteins, the crystallins. Deamidated crystallins are increased in the insoluble proteins and may contribute to cataracts. Deamidation has been shown in vitro to alter the structure and decrease the stability of human len...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904749/ https://ncbi.nlm.nih.gov/pubmed/20188088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2010.02.007 |
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