High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension

Pulmonary hypertension is associated with reduced nitric oxide bioavailability and early mortality in sickle cell disease (SCD). We previously demonstrated that placenta growth factor (PlGF), an angiogenic factor produced by erythroid cells, induces hypoxia-independent expression of the pulmonary va...

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Autors principals: Sundaram, Nambirajan, Tailor, Anitaben, Mendelsohn, Laurel, Wansapura, Janaka, Wang, Xunde, Higashimoto, Tomoyasu, Pauciulo, Michael W., Gottliebson, William, Kalra, Vijay K., Nichols, William C., Kato, Gregory J., Malik, Punam
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Red Cells, Iron, and Erythropoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904575/
https://ncbi.nlm.nih.gov/pubmed/20335221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-244830
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