High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension

Pulmonary hypertension is associated with reduced nitric oxide bioavailability and early mortality in sickle cell disease (SCD). We previously demonstrated that placenta growth factor (PlGF), an angiogenic factor produced by erythroid cells, induces hypoxia-independent expression of the pulmonary va...

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Detalhes bibliográficos
Main Authors: Sundaram, Nambirajan, Tailor, Anitaben, Mendelsohn, Laurel, Wansapura, Janaka, Wang, Xunde, Higashimoto, Tomoyasu, Pauciulo, Michael W., Gottliebson, William, Kalra, Vijay K., Nichols, William C., Kato, Gregory J., Malik, Punam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904575/
https://ncbi.nlm.nih.gov/pubmed/20335221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-09-244830
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