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A Fluorescent Window Into Protein Folding and Aggregation in Cells

Evolutionary selective pressures have tuned the efficiency of the protein-folding reaction in the crowded complex environment in the cell. Nevertheless, the fidelity of folding is imperfect, leading to off-pathway intermolecular interactions that compete with proper folding and to consequent formati...

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Bibliographic Details
Main Authors: Ignatova, Zoya, Gierasch, Lila M.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904565/
https://ncbi.nlm.nih.gov/pubmed/19118672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0091-679X(08)00603-1
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