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Orthogonal Cross-Seeding: An Approach To Explore Protein Aggregates In Living Cells

Protein aggregation is associated with the pathology of many diseases, especially neurodegenerative diseases. A variety of structurally polymorphic aggregates or preaggregates including amyloid fibrils is accessible to any aggregating protein. Preaggregates are now believed to be the toxic culprits...

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Autori principali: Hinz, Justyna, Gierasch, Lila M., Ignatova, Zoya
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896251/
https://ncbi.nlm.nih.gov/pubmed/18330996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800002j
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