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Inhibition of protein aggregation in vitro and in vivo by a natural osmoprotectant

Small organic molecules termed osmolytes are harnessed by a variety of cell types in a wide range of organisms to counter unfavorable physiological conditions that challenge protein stability and function. Using a well characterized reporter system that we developed to allow in vivo observations, we...

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Detalhes bibliográficos
Main Authors: Ignatova, Zoya, Gierasch, Lila M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569168/
https://ncbi.nlm.nih.gov/pubmed/16899544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603772103
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