Epidermal Growth Factor Receptor Polymorphisms and Risk for Toxicity in Paediatric Patients Treated with Gefitinib

PURPOSE: To investigate associations between germline genetic variations in the epidermal growth factor receptor (EGFR) and toxicity in paediatric patients treated with gefitinib. PATIENTS AND METHODS: Gefitinib treatment and toxicity data from 5 paediatric clinical trials were combined. EGFR genoty...

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Detalhes bibliográficos
Main Authors: McKibbin, Trevor, Zhao, Wei, Tagen, Michael, Daw, Najat C., Furman, Wayne L., McGregor, Lisa M., Geyer, J. Russell, Allen, Jeffrey W., Stewart, Clinton F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904359/
https://ncbi.nlm.nih.gov/pubmed/20621735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2010.05.007
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