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A Single-Arm Pilot Phase II Study of Gefitinib and Irinotecan in Children with Newly Diagnosed High-Risk Neuroblastoma
BACKGROUND: Gefitinib potently inhibits neuroblastoma proliferation in vitro, and the gefitinib/irinotecan combination shows greater than additive activity against neuroblastoma xenografts. This Phase II pilot study estimated the rate of response to two courses of intravenous irinotecan plus oral ge...
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| Autori principali: | , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3232294/ https://ncbi.nlm.nih.gov/pubmed/21796439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-011-9724-3 |
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