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Protection of Pancreatic β-Cells by Group VIA Phospholipase A(2)-Mediated Repair of Mitochondrial Membrane Peroxidation
Mitochondrial production of reactive oxygen species and oxidation of cardiolipin are key events in initiating apoptosis. We reported that group VIA Ca(2+)-independent phospholipase A(2) (iPLA(2)β) localizes in and protects β-cell mitochondria from oxidative damage during staurosporine-induced apopto...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903934/ https://ncbi.nlm.nih.gov/pubmed/20463052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0016 |
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