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Inhibition of Ca(2+)-Independent Phospholipase A(2) Results in Insufficient Insulin Secretion and Impaired Glucose Tolerance
Islet Ca(2+)-independent phospholipase A(2) (iPLA(2)) is postulated to mediate insulin secretion by releasing arachidonic acid in response to insulin secretagogues. However, the significance of iPLA(2) signaling in insulin secretion in vivo remains unexplored. Here we investigated the physiological...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917620/ https://ncbi.nlm.nih.gov/pubmed/15471944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2004-0169 |
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