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Disruption of G1-phase phospholipid turnover by inhibition of Ca(2+)-independent phospholipase A(2) induces a p53-dependent cell-cycle arrest in G1 phase

The G1 phase of the cell cycle is characterized by a high rate of membrane phospholipid turnover. Cells regulate this turnover by coordinating the opposing actions of CTP:phosphocholine cytidylyltransferase and the group VI Ca(2+)-independent phospholipase A(2) (iPLA(2)). However, little is known ab...

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Detalhes bibliográficos
Main Authors: Zhang, Xu Hannah, Zhao, Chunying, Seleznev, Konstantin, Song, Keying, Manfredi, James J., Ma, Zhongmin Alex
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917323/
https://ncbi.nlm.nih.gov/pubmed/16492706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.02821
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