Inhibition of Ca(2+)-Independent Phospholipase A(2) Results in Insufficient Insulin Secretion and Impaired Glucose Tolerance

Islet Ca(2+)-independent phospholipase A(2) (iPLA(2)) is postulated to mediate insulin secretion by releasing arachidonic acid in response to insulin secretagogues. However, the significance of iPLA(2) signaling in insulin secretion in vivo remains unexplored. Here we investigated the physiological...

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Hlavní autoři: Song, Keying, Zhang, Xu, Zhao, Chunying, Ang, Natasha T., Ma, Zhongmin Alex
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917620/
https://ncbi.nlm.nih.gov/pubmed/15471944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2004-0169
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