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Inducible Nitric Oxide Synthase Deficiency in Myeloid Cells Does Not Prevent Diet-Induced Insulin Resistance

Recent findings denote an important contribution of macrophage inflammatory pathways in causing obesity-related insulin resistance. Inducible nitric oxide synthase (iNOS) is activated in proinflammatory macrophages and modestly elevated in insulin-responsive tissues. Although the benefits of systemi...

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Autors principals: Lu, Min, Li, PingPing, Pferdekamper, Jan, Fan, WuQiang, Saberi, Maziyar, Schenk, Simon, Olefsky, Jerrold M.
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903908/
https://ncbi.nlm.nih.gov/pubmed/20444886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0462
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