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SOCS-1 Deficiency Does Not Prevent Diet-Induced Insulin Resistance
Obesity is associated with inflammation and increased expression of suppressor of cytokine signaling (SOCS) proteins, which inhibit cytokine and insulin signaling. Thus, reducing SOCS expression could prevent the development of obesity-induced insulin resistance. Using SOCS-1 knockout mice, we inves...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3204362/ https://ncbi.nlm.nih.gov/pubmed/18929539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.09.158 |
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