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SOCS-1 Deficiency Does Not Prevent Diet-Induced Insulin Resistance

Obesity is associated with inflammation and increased expression of suppressor of cytokine signaling (SOCS) proteins, which inhibit cytokine and insulin signaling. Thus, reducing SOCS expression could prevent the development of obesity-induced insulin resistance. Using SOCS-1 knockout mice, we inves...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Emanuelli, Brice, Macotela, Yazmin, Boucher, Jérémie, Kahn, C. Ronald
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204362/
https://ncbi.nlm.nih.gov/pubmed/18929539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.09.158
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