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Sequential immunization with heterologous chimeric flavivirus induces broad-spectrum cross-reactive CD8(+) T-cell responses
Flavivirus vaccines based upon the ChimeriVax™ technology contain the nonstructural genes of the yellow fever (YF) vaccine and the prM and E genes of heterologous flaviviruses such as Japanese encephalitis (JE) and West Nile (WN) viruses. These chimeric vaccines induce both humoral and cell mediated...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903744/ https://ncbi.nlm.nih.gov/pubmed/20536361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/653486 |
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