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Altered effector functions of virus-specific and -cross-reactive CD8(+) T cells in mice immunized with related flaviviruses

Memory cross-reactive CD8(+) T cell responses may induce protection or immunopathology upon secondary viral challenge. To elucidate the potential role of T cells in sequential flavivirus infection, we characterized cross-reactive CD4(+) and CD8(+) T cell responses between attenuated and pathogenic J...

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Pubblicato in:Eur J Immunol
Autori principali: Trobaugh, Derek W., Yang, Liyan, Ennis, Francis A., Green, Sharone
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486265/
https://ncbi.nlm.nih.gov/pubmed/20213733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200839108
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