Establishment and Characterization of a Model of Acquired Resistance to Epidermal Growth Factor Receptor Targeting Agents in Human Cancer Cells

PURPOSE: The epidermal growth factor receptor (EGFR) is recognized as a key mediator of proliferation and progression in many human tumors. A series of EGFR specific inhibitors have recently gained FDA approval in oncology. These strategies of EGFR inhibition have demonstrated major tumor regression...

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מידע ביבליוגרפי
Main Authors: Benavente, Sergio, Huang, Shyhmin, Armstrong, Eric A., Chi, Alexander, Hsu, Kun-Tai, Wheeler, Deric L., Harari, Paul M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903727/
https://ncbi.nlm.nih.gov/pubmed/19190133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2068
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