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p53 modulates acquired resistance to EGFR inhibitors and radiation

There is presently great interest in mechanisms of acquired resistance to EGFR inhibitors that are now being used widely in the treatment of a variety of common human cancers. To investigate these mechanisms we established EGFR inhibitor resistant clones from non-small cell lung cancer cells. A comp...

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Autors principals: Huang, Shyhmin, Benavente, Sergio, Armstrong, Eric A., Li, Chunrong, Wheeler, Deric L., Harari, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3229180/
https://ncbi.nlm.nih.gov/pubmed/22068033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0128
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