Eksport udført — 
Loading...

Design, Synthesis, and Biological Evaluation of Resveratrol Analogues as Aromatase and Quinone Reductase 2 Inhibitors for Chemoprevention of Cancer

A series of new resveratrol analogues were designed and synthesized and their inhibitory activities against aromatase were evaluated. The crystal structure of human aromatase (PDB 3eqm) was used to rationalize the mechanism of action of the aromatase inhibitor 32 (IC(50) 0.59 µM) through docking, mo...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Sun, Bin, Hoshino, Juma, Jermihov, Katie, Marler, Laura, Pezzuto, John M., Mesecar, Andrew D., Cushman, Mark
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903642/
https://ncbi.nlm.nih.gov/pubmed/20558073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.05.042
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!