Parallel in Vivo and in Vitro Selection Using Phage Display Identifies Protease-dependent Tumor-targeting Peptides

We recently developed activatable cell-penetrating peptides (ACPPs) that target contrast agents to in vivo sites of matrix metalloproteinase activity, such as tumors. Here we use parallel in vivo and in vitro selection with phage display to identify novel tumor-homing ACPPs with no bias for primary...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Whitney, Mike, Crisp, Jessica L., Olson, Emilia S., Aguilera, Todd A., Gross, Larry A., Ellies, Lesley G., Tsien, Roger Y.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Enzymology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903386/
https://ncbi.nlm.nih.gov/pubmed/20460372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138297
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы