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In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer
Activatable cell penetrating peptides (ACPPs) are novel in vivo targeting agents comprised of a polycationic cell penetrating peptide (CPP) connected via a cleavable linker to a neutralizing polyanion (Fig. 1A). Adsorption and uptake into cells are inhibited until the linker is proteolyzed1–3. An AC...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
2009
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796841/ https://ncbi.nlm.nih.gov/pubmed/20023745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b904890a |
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