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In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity()

Thrombin and other coagulation enzymes have been shown to be important during atherosclerotic disease development. Study of these proteases is currently limited because of lack of robust molecular imaging agents for imaging protease activity in vivo. Activatable cell penetrating peptides (ACPPs) hav...

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Detalhes bibliográficos
Main Authors: Olson, Emilia S., Whitney, Michael A., Friedman, Beth, Aguilera, Todd A., Crisp, Jessica L., Baik, Fred M., Jiang, Tao, Baird, Stephen M., Tsimikas, Sotirios, Tsien, Roger Y., Nguyen, Quyen T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689578/
https://ncbi.nlm.nih.gov/pubmed/22534729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ib00161f
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